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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01c2ebe43e1912aa7b5656f7c5b36f4d899c52094a8473ecd3270ac6276ec29c' 
  AND token = 'JaEnztl6Sg6NJDw0VsL29V84xFDoAdL1RnwN24SRsHg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}