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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b242a6cbfda1ddffb33600e2adf4f38945a08f88bd6c67250a8419556d466de4' 
  AND token = 'h7JqaFTbouau12buscsp75cHW3gqqPrX9awUfAmZK6A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}