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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88179b65aaf24b4b08727ab8521577c4c2e5e65c967b58ba19c75f1c0d425275' 
  AND token = 'eMhOX+MjTUN8lbU+reK+4DqouyA81LsOFwvAIuWST3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}