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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad230cfd8d78109c942ce6effec76f39cb6bf91031de77c3d107b0c352ed615' 
  AND token = '0OdB/dv5sy4QSsrko+Mq17PsB1hGgkLGlYUF3Sexj2A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}