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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5a78926252eefb02deb7cb0fd14520b34b8539eed8ef3c79c2674af31ac8631' 
  AND token = '0/3iziYZTEIavjv/foUBQWoJbCInxLyp69qsX2Xo7k8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}