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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8cb50152d79c406608988a5c1163b4d2007279d4b9e4c67cb0b2c006bd784c4' 
  AND token = '3odu64GmMsmRS49y5+B+4zqdk0asOKA6jphgW2ufi2M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}