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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60b83a9833b80b7b7cd6d6459821a86d8b3504d2d51d0221e59bc73bc6805305' 
  AND token = 'LIOpVL3i3ATc2h6PR0k4IikFH6+N9KyKUGvsRpbvKbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}