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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1b22a7e808c07e91fd333ccca0c6176195e3a0e1b8691c9da7e3c7f44308d75' 
  AND token = 'FfGDAAFE8ZY90ySgavrBS8E7hgfeUxwWAKR/1QxpMAg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}