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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c6a5cefccc71d44b65806dc96485f8dd2440114c73f1194ad28f931a9113307' 
  AND token = 'LC/+34nENNATpeQd4W673/ECcSgUvJJqE3XzwLzj0AI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}