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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80506207e8e85d5e458ed9bbc879aa2e3c6b273dc8efc292fe537f496c83e961' 
  AND token = '0GfaV0TVTdw/46a6/cKnTcV741L/50z5/0Si9JprdQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}