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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '381f2f26c8c25f9b06b56e9688dacb3886df4c5162b7eb3e413db3f3a10add71' 
  AND token = 'ZcNFx7ezWMCVBq3hnywHZmwiSSrdAU4wHYj1N1qA0h4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}