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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f446be52d8b9745785c23fd5452383aec38e93c776daf070ad2de3643de885f2' 
  AND token = '2qU1eQpUxw+Ev0GoN2SQeamTJALMNbA0hUT3hzGmBE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}