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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7bd4193204056e071763e85e8344a0a4ee9414ec07ef5ebbd2706d583ee9734' 
  AND token = '+uY97YRGw34UsLHJTO1uUbsOAv2I8+IhmBz2UZ5kmRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}