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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5385e9a37e408f83d811b6d7405d1d7c52cd3a2172ad4dafc714405e6123ce7a' 
  AND token = '8UZ5qtdIoSlMRxo8tV1K4ARg3JFZS4ooUGiokF/4ZqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}