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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e555227c581d2e664ba77e3a807bc3a9832d5c0e82c3836cf3949ede65c7d553' 
  AND token = 'oG04WPsRoiFMyKvzHakR5r0bvmCGiGQN4NUEzxA9Umg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}