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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57373fe5d21a9c5d0dbc19db702c679f993cb0ebf42f29256f765eeb22ad35ac' 
  AND token = 'PEvN5Np1ehmhzauJPfKw/2AeTtWTRB950DrGpvQhCW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}