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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484f0dffdde3289540793e96a8e3965ef6a09977707cb47bb1c36ca4ae17519d' 
  AND token = 'ZWICKA8ex4EldmhIUp+t7GCm0T8PPOZeKZ/8ecPL2N0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}