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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3aa2fc281f0b46da0d02a2750c9e9480b1fe5b4f160e4a9bbd26eca52c3d437' 
  AND token = 'ya4NOCY+OGquj4osGCN+lCso8jbedFw7SGIyeN1xQx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}