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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74150e49b07e3e566a2d2c02d07bc3135f78298f1b068569e0578da8b3014bf4' 
  AND token = 'dqiWvsdTEjYSNTsKWI9rPi21k9eIL+gbPVUADapcnms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}