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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bcb6fa9a7ac3a6431356ac0db17769c14b70537c325bda4dae8e4e448a1bd05' 
  AND token = 'jTUJ9DefPd2wUmjMnpGQeng7TnEfk1ADAf7+Wh+Kxkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}