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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7fe5c6ae0361ee641b256c177bbe7f0fb0d19e4dd79cdfdf0f5376740390785' 
  AND token = 'qHuwNWS2gs6SvBlnubuT+w/dnJW5SSfLUny3sns/qTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}