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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2cce05c9e4b05d62e907e84cd7418a42652d33dbac79bf66507580dcde848c4' 
  AND token = 'IZddxlHL5H4XF4PqyDqT0txKW7aXu7JFQfRsJ4ltO0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}