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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af8a31a75c20002ae1db8aa4e8120082b58fd910b2635899c6b6571d7dd92792' 
  AND token = 'b6jQ+p+8zWBjV3ELMZvISHeNABgRAdK09aTQOkMKAKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}