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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a7a51b46d4a638148928a59b0777eb03db973748078122e3fc7125e65bd33c6' 
  AND token = 'f7jLSXAAC4gysrGZATXVZ9fL8UljqPb9JV0sJ08sQ1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}