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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc8fd996bc894d50b273b143a69c8d3172f44a446d2fc68b8a004334d573bc73' 
  AND token = 'nEq9fZ9Fs/Qmda1ZFFiOKUshmduGdsCh5Jf0AAUAFY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}