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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b882366f12f04ad198f5534f28c344a589c655cfc8c832281b2329f09ace9129' 
  AND token = 'b/ue6Qxsx5Ru+dTm1sAJsGzI1W2UyCRXxiovViY8U48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}