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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66bce6c6fbf341f40139b14a8a9b20311cffbaf63db76f8c323ca0a9c8a31667' 
  AND token = 'Ltzz/NwFwwQsZa+qgkMe49hhD0g4V1wnsHNSrahJpOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}