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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '481a0617b6f1038d572b0decba5ede71ceaeee2130af33f5baee53eb679c4379' 
  AND token = 'lIOqy7rSnuO2XSykAtZ4y06LiwMx+K8bj/LRJpw54+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}