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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a39fe3f3f46229c80be2a8572035c58d1e6d599f564d26fb2790637cf7097fd5' 
  AND token = 'tAJ2HEfFY3eFOeu2NCrDUukIRLp0ELncwEgqIrjLAcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}