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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c5d3a0632eefb31edd2c4ecda21043353743bd765275b827d8fdb9fd191b3da' 
  AND token = 'dZGdjpzZc8VJcv4xMe9VNOUpfpN9Vdo03dW1dMNj4YU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}