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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '347fa778fa7dd2270cba65fc96b7abdf1b9c3acfc91596f3d24ffda25eda1ca8' 
  AND token = 'BFX8WTCTajIQyRTO7GBtLHs6dSvLt3c+IRnKbRhTEhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}