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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cf5946f2df3c7dca2bb8df0a1e543e2a38016dcf34e56e36412a37159a10911' 
  AND token = '7nr47OjqiNT+LFknu9601aj57Mi5kcf7uJCqYl3Jw4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}