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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4f610d48789017562caca175f61ac548b457be1843c0cfc9e3ff44251a3831e' 
  AND token = '0IOT8OzRF5PDRi4P1RFmdxKmQv3ws7P0zbM9RsNJvHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}