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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8afe3efbfc402aae363780b534cc3221deba37ce97cedb0ca126299b16175f0f' 
  AND token = 'ocN2B9eKt6eI3PCwQ7U5KgATAg7PF6C/3iFGQEvj/KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}