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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '980d46deedd101d14a050892a5da112860ab922115f1d0829a63b333c21d5510' 
  AND token = 'kRUI3JscrdKsA5RM+pWndMzYbBB0WGiXAYlqNoss9So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}