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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08bf16a4a1e2ed9ab43ad117dbf0b738c3f7522cf8dd4870214e2a983240a440' 
  AND token = 'VzHMd6Ky1sLjHUCngfeLjPWqRo411G8+XOfxIdvKxc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}