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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1583ec041440f065066e04c56d077236a1519c39249660d620847d58f72068f7' 
  AND token = 'nbc1d/KmNPLxR73ZhG/1DB6MUZSlkPPQE+c4FzWxU4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}