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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c4bddffa6bcd79e73db892dd70899caa225a425dffc6261ed8ecaa2a9f7c483' 
  AND token = 'f1Ym3+OnDLWrA67NrK8YU6pqHemBtLZJ11/8OD62MwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}