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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f595361db8490d1d9913e672b357d197c29fe4cd705342f07c556214731b10' 
  AND token = 'SQ2Y+s/VzmU9pznA1dPiLP0EynV8gOjfgUIWVV673/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}