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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad22838563546633ff26c49fc8b7f8c01ad4c7d8c3348bb004d0a6085cd54071' 
  AND token = 'EwViocJLiKqv7mK/KYb0u6V48yzU6LVheGo82dLk8bc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}