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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2262e4c1476052071cf3d1e59a7e544113cfa729805f2266271dbdd8cd0a3b6' 
  AND token = 'JOc3gZZSjxlnlBtoYW+WyQGi52om2cQse5hVGBcn2/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}