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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfc0ace12971f7a08f6f7d1f3e6f85e05333212c16bf3e68ab607318f0043f22' 
  AND token = 'N2+5gYDvMiwlw6INPsOVD663b/ivO2vbjfHgtV8jGjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}