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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57dc452d49d695c8a13da426ae1206de5a346bee2fc314f24f401cfd1c212197' 
  AND token = '190zoqZ5Im0NNrBlFIo3qzIAtHtmwKdWpSlQOSvn0ls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}