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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b7dba8387eccc06afd688203dd610e3226cc3c9c5fa640d616ac4c809c7d41a' 
  AND token = 'd2raA8X5SioFIiBIkRbdBN5qFxahZkeKgHRAWdahoL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}