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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88c6fb50939914d66e647bc6c3549657c5e45e8a9451976e5b2a19ba1eade3c9' 
  AND token = 'FOxq+yF8Itk7kTQc8y+C7emIpRU3stpjP2PjBrnLUIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}