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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf192ae9c475688cc16780b114d977987a7fc946c053fa0721329454af9765da' 
  AND token = 'GWiMDqJYM41ugUGvdLiB7x7QFl+npyeS8AxcSDzY1Bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}