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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '547da4cfbbfa1705e7ec01e3e0402d67a31183b7df7a3b9ed87a1946e2c66d91' 
  AND token = 'mH3B07zI4C+Zjs/A7niDAlNZzhz9dWns5EBfNFqAKvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}