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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e87b45d7bed1047b35b4a63b60a61e68b7760512f4f9e5c7d65faa15ac3be0' 
  AND token = 'H5Yl3Z+DitIvQ6jkY2NYnkWeZZn45j2fNtIGV/TUlyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}