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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4726d6b88a15b2f51643a877e940a54004e434bf5263794ce97be2a6b46400de' 
  AND token = '2jmbmgsIVuElfOs1BG+vc/iBbb86et+Il7CLZlTdOBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}