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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '19afd3f7d71fed0780266b6c72b07e00dfed40b4c526115ae3ce31441180ce72' 
  AND token = 'mSaHmUDwlCnmPuwi1Uo+xrSBBr9cd7XUZoJr1T1Frh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}